EFFECTIVNESS OF THE GNRH ANALOGUE DESLORELIN AS A REVERSIBLE CONTRACEPTIVE IN A NEOTROPICAL PRIMATE, THE COMMON MARMOSET CALLITHRIX JACCHUS (MAMMALIA: PRIMATES: CALLITRICHIDAE)

Deslorelin is a synthetic GnRH analogue, which is being used as a contraceptive in animals by acting as a gonadal suppressant.The product Suprelorin (Virbac, Australia) contains deslorelin as a biocompatible, slow release subcutaneous implant.The continuous release of deslorelin provokes a down-regulation of GnRH receptors, and subsequently, inhibi

Atherosclerosis retains the leading position among the causes of global morbidity and mortality worldwide, especially in the industrialized countries.Despite the continuing efforts to investigate disease pathogenesis and find the potential points of effective therapeutic intervention, our understanding of atherosclerosis mechanisms remains limited.

Telomere maintenance is one of the mechanisms ensuring indefinite divisions of cancer and stem cells.Good understanding of telomere maintenance mechanisms (TMM) is important for studying cancers and designing therapies.However, molecular factors triggering selective activation of either the telomerase dependent (TEL) or the alternative lengthening